I’d say the great unknown of all the great unknowns viz immigration reform, or amnesty and open borders as the more cynically inclined are wont to call it, is what will the consequences of a mass demographics shift in the age of multiculturalism be compared to such when the dynamics of the melting pot ruled? Let’s face it, the two belief systems offer and promote quite different views on the nature of people and nations and the role of government - and America became great and powerful under the latter - will it remain great and powerful under the former? No one knows the answer to that question - people are making a lot of assumptions, but ultimately it’s all guesswork.
I tend to believe immigration under a multiculturalist ethos inculcates a neo-liberal world view, especially among ethnicities and cultures not directly connected to the Western tradition, and therefore the country is doomed to move left in its politics, although that shift could prove temporary if the GOP manages the wherewithal to adapt - big ‘if’ there. This is troubling because I don't believe great countries can be governed from the left - the sympathies and ‘causes’ which stimulate the neo-liberal may work in unimportant places like Sweden [although recent events there throw that into question] but a superpower is by necessity fuelled by something altogether different.
In short, neo-liberals, progressives if you wanna call them that, don't want to live in a great and powerful country because such creatures perforce embody things, do things, become responsible for things that conflict with and often outright contradict the qualities and beliefs that liberals see as defining them - and therefore either wilfully or as simple consequence of the sympathies they by nature promote the liberal seeks to undermine the offending power.